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, 1993). One of the proteins involved in this RNP formation is the nuclear-resident PCBP2, which binds to the S-L I structure with increased affinity when the viral polymerase precursor, 3CD, is also present near the 5��-terminus of the RNA, forming a ternary complex (Gamarnik and Andino, 1997, 2000; Parsley et al., 1997). On the opposite terminus of the genome, PABP1 associates with the g

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